Author

Y. Kikuchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 3 Pathology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 4 Organism:rat· 3 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

H. Kondo· 4 shared H. Senoh· 4 shared K. Misumi· 4 shared K. Takanobu· 4 shared M. Saito· 4 shared M. Suzuki· 4 shared S. Hirai· 4 shared S. Yamano· 4 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersPharmacology & Toxicology

H. Kondo

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts

J. Lachat, G. Lextrait, R. Jouan, A. Boukherissa, A. Yokota, S. Jang, K. Ishigami, R. Futahashi, R. Cossard, D. Naquin, V. Costache, L. Augusto, P. Tissiere, E. G. Biondi, B. Alunni, , P. Mergaert

The paper identifies hundreds of antimicrobial peptides in the insect gut that create a selective barrier for symbionts, with resistance mechanisms crucial for colonization.

bioRxiv · Oct 16, 2023Microbiology

Transposon sequencing reveals the essential gene set and genes enabling gut symbiosis in the insect symbiont Caballeronia insecticola

R. Jouan, G. Lextrait, J. Lachat, A. Yokota, R. Cossard, D. Naquin, T. Timtchenko, Y. Kikuchi, T. Ohbayashi, P. Mergaert

This study uses transposon sequencing to identify essential genes and gut-specific nutrients in the insect symbiont Caballeronia insecticola.

bioRxiv · Sep 7, 2023 · PreprintMicrobiology

Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study

S. Yamano, Y. Goto, T. Takeda, S. Hirai, Y. Furukawa, Y. Kikuchi, T. Kasai, K. Misumi, M. Suzuki, K. Takanobu, H. Senoh, M. Saito, H. Kondo, Y. Umeda

This study investigates pulmonary lesions in rats exposed to titanium dioxide nanoparticles, identifying a new lesion type called pulmonary dust foci associated with pneumoconiosis-like effects.

bioRxiv · Mar 31, 2022Pathology

Dose-response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats

T. Takeda, S. Yamano, Y. Goto, S. Hirai, Y. Furukawa, Y. Kikuchi, K. Misumi, M. Suzuki, K. Takanobu, H. Senoh, M. Saito, H. Kondo, G. Daghlian, Y. K. Hong, Y. Yoshimatsu, , Y. Umeda

This study investigates the dose-response relationship of pulmonary disorders caused by inhalation of CWAAP-A in rats, finding a LOAEC of 1 mg/m3 and reversible damage at 1 mg/m3 with gender differences in recovery.

bioRxiv · Dec 26, 2021Pharmacology & Toxicology

Lack of pulmonary fibrogenicity and carcinogenicity of titanium dioxide nanoparticles in 26-week inhalation study in rasH2 mouse model

S. Yamano, T. Takeda, Y. Goto, S. Hirai, Y. Furukawa, Y. Kikuchi, T. Kasai, K. Misumi, M. Suzuki, K. Takanobu, H. Senoh, M. Saito, H. Kondo, Y. Umeda

This study shows titanium dioxide nanoparticles do not cause lung fibrosis or cancer in rasH2 mice after 26 weeks of inhalation exposure up to 32 mg/m3.

bioRxiv · Dec 23, 2021Pharmacology & Toxicology

Pathological characteristics of pulmonary toxicity in F344 rats exposed by inhalation to cross-linked water-soluble acrylic acid polymers

S. Yamano, T. Takeda, Y. Goto, S. Hirai, Y. Furukawa, Y. Kikuchi, K. Misumi, M. Suzuki, K. Takanobu, H. Senoh, M. Saito, H. Kondo, Y. Kobashi, K. Okamoto, T. Kishimoto, Y. Umeda

This study examines lung damage in rats exposed to cross-linked water-soluble acrylic acid polymers (CWAAPs) via inhalation and intratracheal instillation, finding similar pathological outcomes between exposure routes.

bioRxiv · Nov 13, 2021Pharmacology & Toxicology

Higher seroprevalence of Entamoeba histolytica than that of HIV-1 at a voluntary counselling and testing centre in Tokyo

Y. Yanagawa, M. Nagashima, H. Gatanaga, Y. Kikuchi, S. Oka, K. Yokoyama, T. Shinkai, K. Sadamasu, K. Watanabe

The paper reports higher seroprevalence of Entamoeba histolytica compared to HIV-1 and syphilis in a Tokyo VCT center, with risk factors including male sex, older age, and syphilis positivity.

bioRxiv · Jan 31, 2019 · PreprintMicrobiology

Extreme genetic signatures of local adaptation during plant colonization

N. Shah, T. Wakabayashi, Y. Kawamura, C. K. Skovbjerg, M.-Z. Wang, Y. Mustamin, Y. Isomura, V. Gupta, H. Jin, T. Mun, N. Sandal, F. Azuma, E. Fukai, U. Seren, S. Kusakabe, , S. U. Andersen

The paper investigates genetic adaptations during the colonization of Japan by Lotus japonicus, identifying genomic regions and candidate genes associated with overwintering and flowering time traits.

bioRxiv · Dec 11, 2018Evolutionary Biology

Galectin-3 and N-acetylglucosamine promote myogenesis and improve skeletal muscle function in the mdx model of Duchenne muscular dystrophy

A. Rancourt, S. Dufresne, G. St-Pierre, J.-C. Levesque, H. Nakamura, Y. Kikuchi, M. S. Satoh, J. Frenette, S. Sato

This study shows that galectin-3 and N-acetylglucosamine enhance myogenesis and improve muscle function in the mdx DMD mouse model.

bioRxiv · Oct 16, 2017Pathology