Author

J. Lafontaine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

A.-M. Mes-Masson· 2 shared D. Provencher· 2 shared E. Carmona· 2 shared F. Rodier· 2 shared K. Rahimi· 2 shared L. Portelance· 2 shared M. Skulimowski· 2 shared S. Cheng· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A.-M. Mes-Masson

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Author profile →

3 papers

Recent·Most cited

A senescence-like state is beneficial for ovarian cancer treatment

M. Skulimowski, L. Calvo Gonzalez, S. Cheng, I. Clement, L. Portelance, Y. Zhan, E. Carmona, J. Lafontaine, M. Deladurantaye, K. Rahimi, D. Provencher, A.-M. Mes-Masson, F. Rodier

This study shows that senescence in ovarian cancer cells after chemotherapy correlates with better patient survival, suggesting senescence could be a therapeutic target.

bioRxiv · Sep 30, 2023 · PreprintCancer Biology

Alcohol-Induced Mucociliary Dysfunction: Role of Defective CFTR Channel Function

L. Rasmussen, D. Stafford, J. LaFontaine, L. Antony, A. Allen, H. Kim, S. V. Raju

This study shows chronic alcohol use reduces CFTR activity and airway surface hydration, impairing mucociliary clearance and increasing respiratory infection risk.

bioRxiv · Jul 17, 2023 · PreprintPharmacology & Toxicology

Cellular senescence is a central response to cytotoxic chemotherapy in high-grade serous ovarian cancer

L. Calvo, S. Cheng, M. Skulimowski, I. Clément, L. Portelance, Y. Zhan, E. Carmona, J. Lafontaine, M. de Ladurantaye, K. Rahimi, D. Provencher, A.-M. Mes-Masson, F. Rodier

The paper shows that chemotherapy induces cellular senescence in high-grade serous ovarian cancer, which correlates with better patient survival.

bioRxiv · Sep 24, 2018 · PreprintCancer Biology