SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4
F. Onodi, L. Bonnet-Madin, L. Meertens, L. Karpf, J. Poirot, S.-Y. Zhang, c. picard, A. Puel, E. Jouanguy, Q. Zhang, J. LeGoff, J.-M. Molina, C. Delaugerre, J.-L. Casanova, A. AMARA, V. Soumelis
This study shows SARS-CoV-2 activates human plasmacytoid pre-dendritic cells (pDC) via UNC93B and IRAK4, leading to interferon and cytokine production.
bioRxiv · Jul 10, 2020Immunology