Author

L. Karpf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. AMARA· 1 shared A. H. Rahman· 1 shared A. Lansky· 1 shared A. M. Leader· 1 shared A. Puel· 1 shared A. Tabachnikova· 1 shared A. Wolf· 1 shared C. Delaugerre· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. AMARA

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Spatial positioning and matrix programs of cancer-associated fibroblasts promote T cell exclusion in human lung tumors

J. A. Grout, P. Sirven, A. M. Leader, S. Maskey, E. Hector, I. Puisieux, F. Steffan, E. Cheng, N. Tung, M. Maurin, R. Vaineau, L. Karpf, M. Plaud, M. Casanova-Acebes, A. Tabachnikova, , H. Salmon

The paper identifies two CAF subsets in human lung tumors that promote T cell exclusion through distinct matrix programs and spatial organization.

bioRxiv · Jan 20, 2022Cancer Biology

SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4

F. Onodi, L. Bonnet-Madin, L. Meertens, L. Karpf, J. Poirot, S.-Y. Zhang, c. picard, A. Puel, E. Jouanguy, Q. Zhang, J. LeGoff, J.-M. Molina, C. Delaugerre, J.-L. Casanova, A. AMARA, V. Soumelis

This study shows SARS-CoV-2 activates human plasmacytoid pre-dendritic cells (pDC) via UNC93B and IRAK4, leading to interferon and cytokine production.

bioRxiv · Jul 10, 2020Immunology