Author

J. McLellan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Galindo· 1 shared A. Herbert· 1 shared A. Kuehne· 1 shared A. Ramamohan· 1 shared A. Tse· 1 shared A. Wang· 1 shared C. Salaun· 1 shared E. McFadden· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Galindo

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2 papers

Recent·Most cited

Engineering, structure, and immunogenicity of a Crimean-Congo hemorrhagic fever virus pre-fusion heterotrimeric glycoprotein complex

E. McFadden, S. Monticelli, A. Wang, A. Ramamohan, T. Batchelor, A. Kuehne, R. Bakken, A. Tse, K. Chandran, A. Herbert, J. McLellan

The paper describes the structure and immunogenicity of a stabilized CCHFV heterotrimeric glycoprotein complex and shows it provides 40% protection against viral challenge in mice.

bioRxiv · Apr 20, 2024 · PreprintMicrobiology

Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation

C. Salaun, H. Takizawa, A. Galindo, K. R. Munro, J. McLellan, I. Sugimoto, T. Okino, N. C. O. Tomkinson, L. H. Chamberlain

This study develops a FRET-based high-throughput screen to identify inhibitors of zDHHC2 auto-acylation, discovering two tetrazole compounds that inhibit both auto-acylation and substrate S-acylation.

bioRxiv · Mar 17, 2022Cell Biology