Locally confined IFNγ production by CD4+ T cells provides niches for murine cytomegalovirus replication in the salivary gland
J. Oderbolz, N. Zangger, L. Zimmermann, I. Sandu, J. Starruss, F. Graw, A. Oxenius
This study shows that CD4+ T cells produce IFNγ locally in clusters near MCMV infection foci in salivary glands, enabling regional protection while allowing continued viral replication.
bioRxiv · Jan 14, 2021 · PreprintImmunology