Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis
D. Moussaoui, J. P. Robblee, D. Auguin, E. B. Krementsova, S. Haase, T. C. A. Blake, J. Baum, J. Robert-Paganin, K. M. Trybus, A. Houdusse
The paper presents the full-length structure of Plasmodium falciparum Myosin A (PfMyoA) and its light chain PfELC, revealing interactions critical for motor function and identifying PfELC as a potential antimalarial target.
bioRxiv · Jun 30, 2020 · PreprintBiochemistry