Author

D. Auguin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Robert-Paganin· 4 shared A. Houdusse· 3 shared D. Moussaoui· 2 shared A. Grinzato· 1 shared C. Chabbert· 1 shared C. Kikuti· 1 shared D. Pathak· 1 shared E. B. Krementsova· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBiophysics

J. Robert-Paganin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-EM structure of the folded-back state of human β-cardiac myosin

A. Grinzato, D. Auguin, C. Kikuti, N. Nandwani, D. Moussaoui, D. Pathak, E. Kandiah, K. M. Ruppel, J. A. Spudich, A. Houdusse, J. Robert-Paganin

The paper reports the 3.6 Å cryo-EM structure of the folded-back IHM state of human β-cardiac myosin, revealing HCM mutation hotspots and structural differences from smooth muscle myosin IHMs.

bioRxiv · Apr 15, 2023 · PreprintBiophysics

Dexamethasone, a direct modulator of AQP2 in Meniere s disease.

R. Mom, J. Robert-Paganin, T. Mom, C. Chabbert, S. Rety, D. Auguin

This study shows dexamethasone directly interacts with AQP2, modulating its water permeability and providing new insights into its mechanism in Meniere's disease treatment.

bioRxiv · Jan 25, 2022 · PreprintBiochemistry

Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis

D. Moussaoui, J. P. Robblee, D. Auguin, E. B. Krementsova, S. Haase, T. C. A. Blake, J. Baum, J. Robert-Paganin, K. M. Trybus, A. Houdusse

The paper presents the full-length structure of Plasmodium falciparum Myosin A (PfMyoA) and its light chain PfELC, revealing interactions critical for motor function and identifying PfELC as a potential antimalarial target.

bioRxiv · Jun 30, 2020 · PreprintBiochemistry

Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

J. Robert-Paganin, D. Auguin, A. Houdusse

This study identifies how different HCM mutations affect cardiac myosin function and auto-inhibition, leading to hypertrophic cardiomyopathy through varied molecular mechanisms.

bioRxiv · May 17, 2018Biophysics