Author

J. Round

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A.-M. Liebhoff· 1 shared B. Langmead· 1 shared C. May· 1 shared C. Morrison· 1 shared E. Stephen-Victor· 1 shared E. Yung· 1 shared F. Teng· 1 shared G. Sharma· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A.-M. Liebhoff

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A Synthetic Cytotoxic T cell Platform for Rapidly Prototyping TCR Function

G. Sharma, J. Round, F. Teng, Z. Ali, C. May, E. Yung, R. Holt

This paper introduces a synthetic cytotoxic T cell platform for rapidly prototyping TCR function, demonstrating successful antigen-specific responses and preservation of antigen-presenting cells.

bioRxiv · Nov 20, 2023Immunology

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

A.-M. Liebhoff, T. Venkataraman, W. R. Morgenlander, M. Na, T. Kula, K. Waugh, C. Morrison, M. Rewers, R. Longman, J. Round, S. Elledge, I. Ruczinski, B. Langmead, H. B. Larman

The paper develops Dolphyn, a machine learning method to improve PhIP-Seq by prioritizing epitopes, increasing antibody-bound peptides from 10% to 31% and reducing synthesized peptides by 78%.

bioRxiv · Jul 30, 2023Bioengineering

Clec12a tempers inflammation while restricting expansion of a colitogenic commensal

J. Round, T. Chiaro, K. Bauer, K. Ost, E. Stephen-Victor, M. Nelson, J. H. Hill, R. Bell, M. Harwood, W. Voth, T. Jackson, K. Klag, R. O'Connell, W. Z. Stephens

This study shows that Clec12a limits inflammation and prevents the expansion of a harmful commensal bacteria, Faecalibaculum rodentium, by enhancing macrophage phagocytosis.

bioRxiv · Mar 16, 2023 · PreprintImmunology