Author

J. S. Schreck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

P. Sulc· 2 shared A. Di Gioacchino· 1 shared F. Hong· 1 shared J. Bridstrup· 1 shared J. Procyk· 1 shared J.-M. Yuan· 1 shared M. Molari· 1 shared R. Monasson· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

P. Sulc

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Author profile →

3 papers

Recent·Most cited

Generative and interpretable machine learning for aptamer design and analysis of in vitro sequence selection

A. Di Gioacchino, J. Procyk, M. Molari, J. S. Schreck, Y. Zhou, Y. Liu, R. Monasson, S. Cocco, P. Sulc

This study uses Restricted Boltzmann Machines to analyze SELEX data for thrombin aptamers, enabling sequence fitness estimation, classification, and novel molecule generation, which is validated experimentally.

bioRxiv · Mar 12, 2022Biophysics

Understanding DNA interactions in crowded environments with a coarse-grained model

F. Hong, J. S. Schreck, P. Sulc

This study uses a coarse-grained model to investigate how crowding affects DNA duplex and hairpin formation, finding that crowders increase melting temperature and enhance hybridization kinetics.

Nucleic Acids Research · Nov 4, 2020Peer-reviewedBiophysics

Investigating the effects of molecular crowding on the kinetics of protein aggregation

J. S. Schreck, J. Bridstrup, J.-M. Yuan

This study extends a protein aggregation model to include macromolecular crowding effects, showing it can speed up, slow down, or have no effect on aggregation kinetics, consistent with experimental data.

bioRxiv · Aug 5, 2020Biophysics