Systems Biologynpj Systems Biology and ApplicationsPeer-reviewed
Understanding flux switching in metabolic networks through an analysis of synthetic lethals
Sowmya Manojna Narasimha, Tanisha Malpani, Omkar S. Mohite…·Karthik Raman
The paper identifies alternate metabolic pathways rerouted during synthetic lethal reaction pairs using a constraint-based optimization approach and applies it to genome-scale models.
5 citations