Author

J. Scharner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Krainer· 1 shared A. S. H. Costa· 1 shared D. M. Voss· 1 shared F. C. Bennett· 1 shared F. Rigo· 1 shared H. Y. Jeon· 1 shared J. E. Wilkinson· 1 shared K.-T. Lin· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Krainer

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1 paper

Recent·Most cited

ASO-based PKM Splice-switching Therapy Inhibits Hepatocellular Carcinoma Cell Growth

W. K. Ma, D. M. Voss, J. Scharner, A. S. H. Costa, K.-T. Lin, H. Y. Jeon, J. E. Wilkinson, M. Jackson, F. Rigo, F. C. Bennett, A. Krainer

This paper demonstrates that ASO-based PKM splice-switching therapy inhibits HCC cell growth by converting PKM2 to PKM1, altering glucose metabolism and reducing tumorigenesis.

bioRxiv · Sep 1, 2020Cancer Biology