TLR5 participates in the TLR4 receptor complex and biases towards MyD88-dependent signaling in environmental lung injury
S. Hussain, C. C. Johnson, J. Sciurba, X. Meng, V. P. Stober, C. Liu, J. Cypher-Daly, K. Bulek, W. Qian, A. Solis, Y. Sakamachi, C. Trempus, J. J. Aloor, K. Gowdy, W. M. Foster, , S. Garantziotis
This study shows TLR5 associates with TLR4 and biases its signaling toward MyD88 in lung injury responses to LPS, hyaluronan, and O3.
bioRxiv · Oct 3, 2019Immunology