TRAF4 is crucial for the propagation of ST2+ memory Th2 cells in IL-33-mediated type 2 airway inflammation
J. Xiao, X. Chen, W. Liu, W. Qian, K. Bulek, L. Hong, W. Miller-Little, X. Li, C. Liu
This study shows TRAF4 is essential for ST2+ memory Th2 cell proliferation in IL-33-driven type 2 airway inflammation, revealing its role in AKT/mTOR and ERK1/2 signaling and gene expression.
bioRxiv · Feb 11, 2023 · PreprintImmunology