Author

J. Sebolt-Leopold

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Abecunas· 1 shared C. Frankowski-McGregor· 1 shared C. Whitehead· 1 shared D. G. Baumann· 1 shared E. Ziemke· 1 shared M. Fallahi-Sichani· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

C. Abecunas

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1 paper

Recent·Most cited

Cancer BiologybioRxivMar 6, 2022

Systematic analysis uncovers SYK dependency in NF1LoF melanoma cells

C. Abecunas, C. Whitehead, E. Ziemke…·M. Fallahi-Sichani

This study identifies SYK as a therapeutic target in NF1LoF melanoma cells, showing that MTX-216, a compound inhibiting both PI3K and SYK, effectively blocks tumor growth.

DOI 10.1158/0008-5472.can-22-0883

humanbulk RNA-seq

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