J. Seemann

RNA scaffolds the Golgi ribbon by forming condensates with GM130

This study shows that GM130 and RNA form condensates that scaffold the Golgi ribbon, and disrupting this interaction disrupts ribbon structure.

ERK-dependent DICER1 phosphorylation promotes open chromatin state and lineage plasticity to mediate tumor progression

The paper shows that phosphorylated DICER1 promotes open chromatin and lineage plasticity in lung adenocarcinomas, independent of miRNAs and EMT.

Turning movements in real life capture subtle longitudinal and preataxic changes in cerebellar ataxia

This study identifies dynamic balance measures during real-life turning movements as sensitive biomarkers for detecting longitudinal and preataxic changes in degenerative cerebellar ataxia.

Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure

This study shows that acute depletion of GRASP55 or GRASP65 does not affect the Golgi ribbon, but chronic degradation of GRASP55 disrupts its lateral connectivity.

TPX2 activation by GM130 controls astral microtubule formation and spindle orientation

This study identifies TPX2 activation by GM130 on mitotic Golgi membranes as critical for astral microtubule formation and spindle orientation.

Towards ecologically valid biomarkers: real-life gait assessment in cerebellar ataxia

This study identifies real-life gait biomarkers for cerebellar ataxia using wearable sensors, showing high accuracy and sensitivity to disease severity.

Environmental DNA survey captures patterns of fish and invertebrate diversity across a tropical seascape

The paper uses eDNA surveys to assess fish and invertebrate diversity across a tropical Caribbean bay, finding significant community differences driven by habitat specialists and wave tolerance.