Author

J. Shifman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Singh· 1 shared D. Thillaivillalan· 1 shared M. Heyne· 1 shared M. J. Smith· 1 shared N. Papo· 1 shared R. C. Killoran· 1 shared S. Singh· 1 shared X. Xu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Singh

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2 papers

Recent·Most cited

RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway

D. Thillaivillalan, S. Singh, R. C. Killoran, A. Singh, X. Xu, J. Shifman, M. J. Smith

The paper identifies RASSF proteins as effectors linking RAS GTPases to the Hippo pathway, showing specificity in binding and regulatory roles.

bioRxiv · Feb 5, 2020Biochemistry

Generating quantitative binding landscapes through fractional binding selections, deep sequencing and data normalization

M. Heyne, N. Papo, J. Shifman

The paper introduces a method to quantify binding free energy changes for thousands of protein mutants using randomization, sequencing, and normalization, applied to BPTI and Bovine Trypsin interactions.

bioRxiv · Jan 3, 2019Biochemistry