Author

M. J. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

R. C. Killoran· 2 shared A. J. Hayes· 1 shared A. K. Simmons· 1 shared A. P. Jones· 1 shared A. Robert· 1 shared A. Singh· 1 shared A. T. King· 1 shared A. T. Lee· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersBiochemistry

R. C. Killoran

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in NF2-related Schwannomatosis

A. P. Jones, M. J. Haley, G. E. Gregory, C. J. Hannan, A. K. Simmons, L. D. Bere, D. G. Lewis, P. Oliveira, M. J. Smith, A. T. King, D. G. Evans, P. Paszek, D. Brough, O. N. Pathmanaban, K. Couper

This study uses imaging mass cytometry to analyze spatial immunological differences in vestibular schwannomas from NF2 SWN patients, revealing niche-dependent T-cell regulation.

bioRxiv · Apr 9, 2024 · PreprintImmunology

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex

I. E. Elkholi, J. Boulais, M.-P. Thibault, H.-D. Phan, A. Robert, L. B. Lai, D. Faubert, M. J. Smith, V. Gopalan, J.-F. Cote

bioRxiv · May 11, 2023Biochemistry

A mechanistic model of malignant transformation in vestibular schwannoma

C. G. Paterson, I. Bozic, M. J. Smith, X. Hoad, D. G. R. Evans

The paper develops a mechanistic model of malignant transformation in vestibular schwannoma, estimating mutation and LOH rates and assessing radiation-induced malignancy risk.

bioRxiv · Oct 3, 2021Cancer Biology

RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway

D. Thillaivillalan, S. Singh, R. C. Killoran, A. Singh, X. Xu, J. Shifman, M. J. Smith

The paper identifies RASSF proteins as effectors linking RAS GTPases to the Hippo pathway, showing specificity in binding and regulatory roles.

bioRxiv · Feb 5, 2020Biochemistry

Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases in parallel

R. C. Killoran, M. J. Smith

This study uses NMR to analyze nucleotide cycling and effector interactions of multiple small GTPases, revealing their activation mechanisms and Mg2+ dependence.

bioRxiv · Mar 27, 2019Biochemistry

The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcoma

A. T. Lee, W. Chew, M. J. Smith, D. C. Strauss, C. Fisher, A. J. Hayes, I. Judson, K. Thway, R. L. Jones, P. H. Huang

This study evaluates the adequacy of tissue microarrays for assessing TIL burden heterogeneity in leiomyosarcoma and finds that 1-3 cores suffice for ordinal categorization but more are needed for accurate absolute counts.

bioRxiv · Sep 10, 2018Cancer Biology