Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity
Z. Inde, C. Yapp, G. N. Joshi, J. Spetz, C. Fraser, B. Deskin, E. Ghelfi, C. Sodhi, D. Hackam, L. Kobzik, B. Croker, D. Brownfield, H. Jia, K. A. Sarosiek
The paper examines age-related changes in ACE2 expression and apoptosis regulation in lung tissue, linking these to differences in COVID-19 severity across age groups.
bioRxiv · Sep 13, 2020Cell Biology