I. Bruchhaus

FoxO factors preserve airway epithelial homeostasis by coordinating adaptive stress responses

The paper shows FoxO factors in Drosophila, mouse, and human airway epithelial cells respond to stressors by nuclear translocation, with FoxO-dependent stress pathways altered in asthma across species.

Proteins differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones influence pathogenicity by different mechanisms

This study identifies two genes, ehhp127 and ehmp8-2, differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones, showing they influence pathogenicity through distinct mechanisms.

A mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression

This study shows that dSirt4 in Drosophila controls lysozyme expression in the intestine, altering microbiota composition and reducing lifespan.

An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells

The paper identifies a novel domain in MSRP6 that mediates Maurer's clefts anchoring and maintenance in P. falciparum, but shows these functions are dispensable for PfEMP1 transport and cytoadherence.