Author

J. Starzyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:variant calling· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

D. Lee· 2 shared H. Wu· 2 shared I. Majumdar· 2 shared K. Xie· 2 shared R. Shan· 2 shared B. Suter· 1 shared H. Nam· 1 shared J. Famiglietti· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

D. Lee

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TESOGENASE, An Engineered Nuclease Editor for Enhanced Targeted Genome Integration

H. Nam, K. Xie, I. Majumdar, S. Yang, J. Starzyk, D. Lee, R. Shan, J. Li, H. Wu

The paper introduces enGager, a system that enhances ssDNA-mediated genome integration by fusing Cas9 with ssDNA-binding proteins, achieving up to 6-fold efficiency improvements for large transgene knock-in.

bioRxiv · Aug 28, 2023 · PreprintBioengineering

Circular single-stranded DNA is a superior homology-directed repair donor template for efficient genome engineering

K. Xie, J. Starzyk, I. Majumdar, K. Rincones, T. Tran, D. Lee, S. Niemi, J. Famiglietti, B. Suter, R. Shan, H. Wu

This paper develops a non-viral system for efficient genome engineering using circular single-stranded DNA (cssDNA) donors, achieving high knock-in efficiency and improved safety compared to viral vectors.

bioRxiv · Dec 1, 2022 · PreprintBioengineering