BiochemistrybioRxiv
Unveiling the antiviral capabilities of targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2
A. Purificacao, S. Silva-Mendonca, L. Cruz…·C. Nonato
This study identifies quinone-based compounds that inhibit HsDHODH and show anti-SARS-CoV-2 activity with low toxicity and nanomolar IC50.
DOI 10.1021/acsomega.3c07845