Author

J. Weare

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Antoszewski· 1 shared A. R. Dinner· 1 shared A. Tokmakoff· 1 shared B. Vani· 1 shared C.-J. Feng· 1 shared E. H. Thiede· 1 shared L. Hong· 1 shared

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2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Antoszewski

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1 paper

Recent·Most cited

Insulin dissociates by diverse mechanisms of coupled unfolding and unbinding

A. Antoszewski, C.-J. Feng, B. Vani, E. H. Thiede, L. Hong, J. Weare, A. Tokmakoff, A. R. Dinner

This study uses molecular dynamics simulations to investigate insulin dimer dissociation mechanisms, revealing multipathway behavior with conformational selection and induced fit as limiting cases.

bioRxiv · Mar 16, 2020Biophysics