Author

J. Weltner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

E.-M. Jouhilahti· 2 shared J. Kere· 2 shared R. Trokovic· 2 shared S. Katayama· 2 shared T. Otonkoski· 2 shared D. Balboa· 1 shared I. Kirjanov· 1 shared J. Sokka· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

E.-M. Jouhilahti

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2 papers

Recent·Most cited

Transient DUX4 expression induces blastomere-like expression program that is marked by SLC34A2

M. Yoshihara, I. Kirjanov, S. Nykänen, J. Sokka, J. Weltner, K. Lundin, L. Gawriyski, E.-M. Jouhilahti, M. Varjosalo, M. H. Tervaniemi, T. Otonkoski, R. Trokovic, S. Katayama, S. Vuoristo, J. Kere

The paper shows that transient DUX4 expression in hESCs generates iBM cells with EGA-like profiles, resembling 8-cell blastomeres and can be enriched using SLC34A2.

bioRxiv · Aug 25, 2021Cell Biology

Human pluripotent reprogramming with CRISPR activators

J. Weltner, D. Balboa, S. Katayama, M. M. Bespalov, K. Krjutskov, E.-M. Jouhilahti, R. Trokovic, J. Kere, T. Otonkoski

This study reprograms human skin fibroblasts into iPSC using CRISPRa, showing that targeting an Alu-motif enhances reprogramming efficiency by improving activation of NANOG and REX1.

bioRxiv · Oct 19, 2017Cell Biology