Author

D. Balboa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

T. Otonkoski· 3 shared H. Ibrahim· 2 shared H. Montaser· 2 shared J. Saarimäki-Vire· 2 shared T. Barsby· 2 shared V. Lithovius· 2 shared A. Tengholm· 1 shared C.-B. Yim· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

T. Otonkoski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Quantifying stem cell derived islet graft volume and composition with FDOPA positron emission tomography

V. Lithovius, S. Lahdenpohja, H. Ibrahim, J. Saarimäki-Vire, L. Uusitalo, H. Montaser, K. Mikkola, C.-B. Yim, T. Keller, J. Rajander, D. Balboa, T. Barsby, O. Solin, P. Nuutila, T. J. Grönroos, T. Otonkoski

This study uses PET tracers to noninvasively monitor stem cell-derived islet graft volume and composition in mice, showing strong correlation with actual graft size and beta cell proportion.

bioRxiv · Dec 18, 2023Cell Biology

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality

H. Ibrahim, D. Balboa, J. Saarimäki-Vire, H. Montaser, O. Dyachok, P.-E. Lund, M. Omar-Hmeadi, J. Kvist, O. P. Dwivedi, V. Lithovius, T. Barsby, V. Chandra, S. Eurola, J. Ustinov, T. Tuomi, , T. Otonkoski

This study shows that RFX6 haploinsufficiency impairs beta cell function, leading to reduced insulin secretion and increased diabetes risk.

bioRxiv · Nov 15, 2023 · PreprintCell Biology

Human pluripotent reprogramming with CRISPR activators

J. Weltner, D. Balboa, S. Katayama, M. M. Bespalov, K. Krjutskov, E.-M. Jouhilahti, R. Trokovic, J. Kere, T. Otonkoski

This study reprograms human skin fibroblasts into iPSC using CRISPRa, showing that targeting an Alu-motif enhances reprogramming efficiency by improving activation of NANOG and REX1.

bioRxiv · Oct 19, 2017Cell Biology