Cancer BiologybioRxiv
The Sec61 translocon is a therapeutic vulnerability in Multiple Myeloma
A. Domenger, C. Choisy, L. Baron…·C. Demangel
This study shows that targeting the Sec61 translocon with mycolactone enhances the effectiveness of bortezomib in killing multiple myeloma cells and reduces toxicity.
DOI 10.15252/emmm.202114740