Predicting developmental relationships of tumor resident and circulating T cells in ovarian cancer
M. dos Santos Carneiro, Y. Bareche, C. Zhao, P. Thebault, K. Rahimi, D. Provenche, V. Samouelian, B. Cormier, J.-F. Cailhier, A.-M. Mes-Masson, S. Petropoulos, J. Stagg, R. Lapointe
The paper identifies developmental relationships between tumor and circulating T cells in ovarian cancer using single-cell transcriptomics and TCR analysis, revealing a differentiation pathway and interactions with Tfh-like cells.
bioRxiv · Feb 28, 2023 · PreprintImmunology