Author

Y. Bareche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. Stagg· 2 shared A.-M. Mes-Masson· 1 shared B. Allard· 1 shared B. Cormier· 1 shared C. Zhao· 1 shared D. Allard· 1 shared D. Provenche· 1 shared E. H. Ma· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. Stagg

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2 papers

Recent·Most cited

The CD73 immune checkpoint promotes tumor cell metabolic fitness

D. Allard, I. Cousineau, E. H. Ma, B. Allard, Y. Bareche, H. Fleury, J. Stagg

This study identifies CD73 as a metabolic regulator in tumor cells, showing it enhances mitochondrial respiration and aspartate biosynthesis, and that targeting CD73 reduces metabolic fitness and genomic stability.

eLife · Jun 1, 2023Peer-reviewedCancer Biology

Predicting developmental relationships of tumor resident and circulating T cells in ovarian cancer

M. dos Santos Carneiro, Y. Bareche, C. Zhao, P. Thebault, K. Rahimi, D. Provenche, V. Samouelian, B. Cormier, J.-F. Cailhier, A.-M. Mes-Masson, S. Petropoulos, J. Stagg, R. Lapointe

The paper identifies developmental relationships between tumor and circulating T cells in ovarian cancer using single-cell transcriptomics and TCR analysis, revealing a differentiation pathway and interactions with Tfh-like cells.

bioRxiv · Feb 28, 2023 · PreprintImmunology