Author

P. Thebault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:clustering· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

R. Lapointe· 2 shared A. A. Benitez· 1 shared A. Cisneros· 1 shared A. Cleret-Buhot· 1 shared A. Emond· 1 shared a. gosselin· 1 shared A. Mejias· 1 shared A. O'Garra· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

R. Lapointe

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Evolution of the CRISPR-Cas9 defence system in Mycoplasma gallisepticum following colonization of a novel bird host

T. Ipoutcha, I. Tsarmpopoulos, G. Gourgues, V. Baby, P. Dubos, G. E. Hill, Y. Arfi, C. Lartigue, P. Thebault, C. Bonneaud, P. Sirand-Pugnet

This study tracks the evolution of CRISPR-Cas9 in Mycoplasma gallisepticum after it shifted to a novel bird host, showing changes in spacers and PAM recognition, and a loss of CRISPR-Cas function over time.

bioRxiv · Mar 14, 2023 · PreprintMicrobiology

Predicting developmental relationships of tumor resident and circulating T cells in ovarian cancer

M. dos Santos Carneiro, Y. Bareche, C. Zhao, P. Thebault, K. Rahimi, D. Provenche, V. Samouelian, B. Cormier, J.-F. Cailhier, A.-M. Mes-Masson, S. Petropoulos, J. Stagg, R. Lapointe

The paper identifies developmental relationships between tumor and circulating T cells in ovarian cancer using single-cell transcriptomics and TCR analysis, revealing a differentiation pathway and interactions with Tfh-like cells.

bioRxiv · Feb 28, 2023 · PreprintImmunology

The pleiotropic effects of the MNK1/2-eIF4E axis support immune suppression and metastasis in a model of postpartum breast cancer.

Q. Guo, M. Bartish, C. Goncalves, F. Huang, S. S. Krisna, S. Preston, A. Emond, V. Z. Li, C. Duerr, Y. Gui, A. Cleret-Buhot, P. Thebault, H. Lefrere, L. Lenaerts, D. Plourde, , W. H. Miller

This study shows that the MNK1/2-eIF4E axis promotes immune suppression and metastasis in postpartum breast cancer by affecting both tumor and non-tumor cells.

bioRxiv · Sep 7, 2020 · PreprintCancer Biology

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in patients receiving antiretroviral therapy: a study from Provir/Latitude45 project.

p. recordon pinson, c. tumiotto, p. bellecave, f. salin, p. thebault, a. gosselin, p. ancuta, m. soares, j.-p. routy, h. fleury

The paper compares HIV-1 proviral DNA sequences in blood and gut-associated lymphoid tissue in ART-treated patients, finding low intra-patient divergence and similar CTL epitope profiles between compartments.

bioRxiv · May 5, 2020Microbiology

Development and Characterization of a Fixed Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Immunological States

M. C. Altman, D. Rinchai, N. Baldwin, M. Toufiq, E. Whalen, M. Garand, B. A. Kabeer, M. Alfaki, S. Presnell, P. Khaenam, A. A. Benitez, F. Mougin, P. Thebault, L. Chiche, N. Jourde-Chiche, , D. Chaussabel

The paper develops a fixed repertoire of blood transcriptome modules based on co-expression patterns across immunological states to provide a stable framework for analyzing and interpreting blood transcriptome data.

bioRxiv · Apr 28, 2020Immunology

The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

S. Elowe, L. Gama Braga, C. Landry, A. Cisneros, M. M. Mathieu, P. Thebault, C. Garand, B. Lottin, P. Garcia, M. Clerc

This study shows the BUBR1 pseudokinase domain enhances PP2A-B56 recruitment to kinetochores, ensuring proper checkpoint silencing and chromosome alignment by modulating phosphorylation.

bioRxiv · Aug 13, 2019 · PreprintCell Biology