Author

J.-R. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Reinberg· 2 shared Y. Jin· 2 shared A. D. Hamilton· 1 shared C. Fu· 1 shared C.-H. Kuo· 1 shared C.-H. Lee· 1 shared C.-R. Chung· 1 shared D. Bready· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

D. Reinberg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Kin selection underpins family dynamics in rural China

Q.-Q. He, M.-Y. Wang, J.-J. Wu, T.-J. Feng, X.-D. Zheng, J.-R. Yu, S.-H. Tang, L.-L. Deng, C. Fu, R. Mace, Y. Tao, T. Ji

The study uses an evolutionary game model and rural Chinese family data to show that kin selection influences family size by adjusting co-resident members to maintain relatedness and inclusive fitness.

bioRxiv · Sep 4, 2023Evolutionary Biology

Rapid and accurate discrimination of Mycobacterium abscessus subspecies based on matrix-assisted laser desorption ionization-time of flight spectrum and machine learning

H.-Y. Wang, C.-H. Kuo, C.-R. Chung, T.-W. Lin, J.-R. Yu, J.-J. Lu, T.-S. Wu

This paper develops a machine learning model using MALDI-TOF spectra to rapidly and accurately identify Mycobacterium abscessus subspecies.

bioRxiv · Sep 6, 2022Microbiology

The H3K36me2 writer-reader dependency in H3K27M-DIPG

J.-R. Yu, G. LeRoy, D. Bready, J. D. Frenster, R. Saldana-Meyer, Y. Jin, N. Descostes, J. M. Stafford, D. G. Placantonakis, D. Reinberg

This study identifies NSD1/2 as key writers and LEDGF/HDGF2 as readers of H3K36me2 in H3K27M-DIPG, showing their role in tumor proliferation and suggesting therapeutic targeting.

bioRxiv · Jan 6, 2021Cancer Biology

Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin

C.-H. Lee, J.-R. Yu, S. Kumar, Y. Jin, S. Kaneko, A. D. Hamilton, D. Reinberg

This study shows that PRC2 activity is controlled by allosteric activation, independent of its chromatin recruitment, and identifies vulnerabilities in PRC2-addicted cancers.

bioRxiv · Oct 28, 2017Biochemistry