BiophysicsbioRxivPreprint
Asymmetric assembly underlies activation mechanism of neuronal GIRK1/2 channels
Takeharu Kawano, Liang Wang, Kim W. Chan…·Diomedes E. Logothetis
This study reveals how asymmetric assembly of GIRK1/2 channels couples lipid-dependent gating to K+ permeation and pharmacological activation through structural and functional analyses.
DOI 10.64898/2026.10.06.756360