NeurosciencebioRxivPreprint
OptoGranules reveal the evolution of stress granules to ALS-FTD pathology
Peipei Zhang, Baochang Fan, Peiguo Yang…·J. Paul Taylor
The paper introduces OptoGranules, a light-inducible system to control stress granule dynamics in cells, showing that persistent stress granule assembly leads to ALS-FTD-like pathology.
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