BiochemistryNature CommunicationsPeer-reviewed
Non-hydrolyzable acetyllysine analogs to study protein acetylation in vitro and in cells
Simon Maria Kienle, Matthias Sigg, Tobias Schneider…·Martin Scheffner
This study introduces ketolysine (KeK), a non-hydrolyzable acetyllysine analog, which remains stable in cells and affects p53-mediated transcription, unlike acetyllysine (AcK) which is deacetylated.
DOI 10.1038/s41467-026-69782-6