NeuroscienceNetwork NeurosciencePeer-reviewed
Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease
Jiaxin Cindy Tu, Peter R Millar, Jeremy F. Strain…·The Dominantly Inherited Alzheimer Network (DIAN)
This study shows hub disruption in ADAD follows a targeted attack pattern, detectable pre-clinically and linked to amyloid beta changes and neuronal activity.