BioengineeringNature CommunicationsPeer-reviewed
CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect
Zachary R. Crook, Gregory P. Sevilla, Pamela Young…·Natalie Winblade Nairn
CYpHER is a targeted protein degradation technology that uses pH-dependent release and the transferrin receptor to deliver drugs to endolysosomes, demonstrating potency and durability in vitro and in vivo.
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