Developmental BiologyCell ReportsPeer-reviewed
Evidence for the digital programming of cellular differentiation: characterization of binary switches in lineage-determining transcription factors
Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch…·Stephen K. Anderson
The paper identifies binary promoter switches in lineage-determining transcription factors, showing mutually exclusive sense/antisense transcription and distinct gene expression patterns in different cell states.