DNA damage alters nuclear mechanics through chromatin reorganisation.
Alia dos Santos, Alexander W Cook, Rosemarie E Gough, Martin Martin Schilling, Nora Aleida Olszok, Ian Brown, Lin Wang, Jesse Arron, Marisa Luisa Martin-Fernandez, Florian Rehfeldt, Christopher P Toseland
This study investigates how DNA damage affects nuclear mechanics through chromatin reorganisation, finding reduced nuclear stiffness and increased chromatin decondensation that may enhance DNA repair.
Nucleic Acids Research · Jan 11, 2021Peer-reviewedBiophysics