Author

Jiajun Yap

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Jiancheng Hu· 1 shared Jimin Yuan· 1 shared Manuela Baccarini· 1 shared Wan Hwa Ng· 1 shared Zhongzhou Chen· 1 shared Zizi Tian· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Jiancheng Hu

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 6, 2017

The Activation of MEK1 by Enhanced Homodimerization Drives Tumorigenesis

Jimin Yuan, Wan Hwa Ng, Zizi Tian…·Jiancheng Hu

This study identifies MEK mutants that drive tumorigenesis through enhanced homodimerization and cross-phosphorylation, highlighting implications for therapy design.

DOI 10.1101/229849

experimental assaywet-lab / biochemical assay

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