Author

Jiayu Chen

BGI Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aijun Jiang· 1 shared Andrew Cearlock· 1 shared Bei‐Bei HeiD· 1 shared Bo WangiD· 1 shared Changwei ShaoiD· 1 shared Chaodi Kong· 1 shared Chaolun LiiD· 1 shared Chen QiiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Aijun Jiang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cross-species molecular stratification enables T cell receptor diagnosis of Parkinson's disease

Jiayu Chen, Xian Xia, Yuruo Zhang, Xiaoge Tong, Yue Liang, Xiangding Fan, Qinghao Meng, Yihong Wei, Gang Hu

This paper stratifies Parkinson's disease patients using T-cell receptor repertoires and develops classifiers that achieve high AUC for subtype diagnosis.

Genome Medicine · Sep 29, 2026Peer-reviewedNeuroscience

Phenotypic CRISPR screening identifies ZBTB10 as a novel regulator of human trophoblast differentiation

Meagan N. Esbin, Rituja Bhowmik, Hanqin Li, Andrew Cearlock, Jiayu Chen, Tomy Tran, Stephen A. McCartney, Ian A. Glass, Dirk F. Hockemeyer, Xavier Darzacq, Fyodor D. Urnov, Robert Tjian, Min Yang

The paper uses an arrayed CRISPR screen to identify ZBTB10 as a regulator of human trophoblast differentiation, showing its role in fusion and hormone secretion.

bioRxiv · Jul 1, 2026 · PreprintCell Biology

The genetic repertoire of the deep sea: from sequence to structure and function

Yang Guo, Zongan Wang, Denghui Li, Lele Wang, Hongxia Lan, Fei Guo, Ziyu Zhao, Zhenjun Liu, Liang Meng, Xuechun Shen, Minxiao Wang, Weishu Zhao, Weijia Zhang, Chaodi Kong, Liuxin Shi, , Yuliang Dong

This study analyzes the genetic diversity of the deep sea, linking protein structures to genetic variants and identifying biotechnologically relevant features.

Cell Host & Microbe · Jun 10, 2026Peer-reviewedBioinformatics