Bei‐Bei He

This study analyzes the genetic diversity of the deep sea, linking protein structures to genetic variants and identifying biotechnologically relevant features.

The paper introduces BioPrinCRISPR, a framework to identify and characterize CRISPR-Cas systems, revealing non-canonical variants and novel domain architectures across bacterial genomes.

This study identifies diverse ribosomally synthesized peptides in the human microbiome and shows some inhibit pathogens and reduce inflammation.

This paper identifies a versatile P450 enzyme, GpeC, capable of catalyzing peptide biaryl macrocyclization across diverse substrates and demonstrates its application in synthesizing natural products.

This study discovers new Avi(Me)Cys-containing cyclopeptide antibiotics effective against drug-resistant bacteria using genome mining and metabolomics.

This study identifies potential cancer-associated 4Fe-4S proteins using three computational traits, discovering 21 novel candidates beyond known ones.