Cell BiologyNature CommunicationsPeer-reviewed
The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells
Arindam Datta, Jessica Jackson, Yaroslav I. Morozov…·Roger A. Greenberg
The paper shows BRCA1-A complex restricts replication fork reversal in ATM-deficient cells, leading to hypersensitivity to Topoisomerase I inhibitors and resistance to PARP1 inhibitors.
2 citations