Pharmacology & ToxicologyProceedings of the National Academy of SciencesPeer-reviewed
High-throughput protein target mapping enables accelerated bioactivity discovery for ToxCast and PFAS compounds
Diwen Yang, Xiaoyun Wang, Jiabao Liu…·Hui Peng
The paper uses high-throughput affinity-selection mass spectrometry to identify protein targets of ToxCast and PFAS compounds, discovering novel interactions and revealing distinct binding patterns of legacy and replacement PFAS.
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