Synthetic BiologyACS Synthetic BiologyPeer-reviewed
Expanding the scope of bacterial CRISPR activation with PAM-flexible dCas9 variants
Cholpisit Kiattisewee, Ava V. Karanjia, Mateusz Legut…·Jesse G. Zalatan
This study evaluates PAM-flexible dCas9 variants for bacterial CRISPR activation and repression, finding trade-offs between PAM flexibility and repression efficiency.
20 citations