Author

John M Hurley

National Institute of Standards and Technology

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Synthetic Biology· 1

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Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1

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Molly WintenbergiD· 1 shared Nina Alperovich· 1 shared Olga B Vasilyeva· 1 shared Samuel W. SchaffteriD· 1 shared

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Molly WintenbergORCID

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Synthetic BiologybioRxivPreprintSep 24, 2025

Genetically encoded RNA strand exchange circuits for programmable protein expression and computation in cells

Samuel W. Schaffter, Olga B Vasilyeva, Molly Wintenberg…·Nina Alperovich

This study demonstrates genetically encoded RNA strand exchange circuits in living cells, showing that in vitro TMSE design principles apply to E. coli but with cellular-specific caveats.

1 citation

E. coliDNA methylation

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