Author

Joseph Barden

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:electronic health records· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Joanna MattisiD· 4 shared Chandni RanaiD· 3 shared Alexander Sajdak· 2 shared Christian R. BurgessiD· 2 shared Hudson Haberland· 2 shared Juan Disla· 2 shared Limei ZhuiD· 2 shared Meiling ZhaoiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersNeuroscience

Joanna MattisORCID

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4 papers

Recent·Most cited

Seizures in a Dravet Syndrome mouse model inhibit the locus coeruleus but locally evoke supraphysiologic norepinephrine release

Meiling Zhao, Yiannos Demetriou, Anam Noor, Joseph Barden, Limei Zhu, Qianyi Yu, Alexander Sajdak, Arnav Akhaury, Chandni Rana, Peilin Yang, Yulong Li, Christian R. Burgess, Sam McKenzie, Paul Kramer, Joanna Mattis

The paper investigates NE release during seizures in a Dravet Syndrome mouse model, finding inhibited LC-NE neuron activity but increased NE release in downstream regions.

bioRxiv · Oct 1, 2026 · PreprintNeuroscience

Characterization and application of hyperthermia-evoked seizures in a mouse model of focal cortical dysplasia

Xiaogang Zhang, Chandni Rana, Ruitao Shen, Tao Yang, Joseph Barden, Hudson Haberland, Mi Jiang, Rida Qureshi, Saif Siddiqui, Alexander Sajdak, Patrick N. Lawlor, Yu Wang, Joanna Mattis

This study shows that hyperthermia reliably triggers seizures in a mouse model of focal cortical dysplasia, enabling testing of therapeutic interventions.

Neurobiology of Disease · Apr 20, 2026Peer-reviewedNeuroscience

The impact of seizures on REM sleep and the cholinergic pedunculopontine nucleus in a mouse model of Dravet Syndrome

Krystal Santiago-Colon, Chandni Rana, Brandon A. Toth, Julia A. Kravchenko, Joseph Barden, Isabella VanHorn, Alex Jack, Alexander Hollier, Rida Qureshi, Hudson Haberland, Juan Disla, Nagham Eldroubi, Saif Siddiqui, Sophie Erb-Watson, Christian R. Burgess, , Joanna Mattis

This study shows seizures impair REM sleep by disrupting cholinergic neurons in the pedunculopontine nucleus in a mouse model of Dravet Syndrome.

bioRxiv · Feb 18, 2026 · PreprintNeuroscience

Medial septum parvalbumin-expressing inhibitory neurons are impaired in a mouse model of Dravet Syndrome

Limei Zhu, Yiannos Demetriou, Joseph Barden, Juan Disla, Meiling Zhao, Joanna Mattis

This study identifies impaired parvalbumin-expressing inhibitory neurons in the medial septum of Scn1a+/- mice, a model of Dravet Syndrome, suggesting a potential contribution to cognitive deficits.

Epilepsia · Jul 7, 2025Peer-reviewedNeuroscience