Author

Joseph R. Sawires

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Eleadah Vidales· 2 shared Jerry YangiD· 2 shared Pradipta GhoshiD· 2 shared Vanessa CastilloiD· 2 shared Adel Adel· 1 shared Annelies Ondersma· 1 shared Celia R. Espinoza· 1 shared Courtney TindleiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Eleadah Vidales

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 13, 2023

Machine Learning Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal Cancers

Saptarshi Sinha, Joshua Alcantara, Kevin Perry…·Pradipta Ghosh

This paper introduces a machine learning framework to identify and target transcriptomic vulnerabilities in colorectal cancer, demonstrating that differentiation therapy selectively eliminates cancer stem cells and reduces recurrence risk.

DOI 10.1101/2023.09.13.557628

humanbulk RNA-seq

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BioinformaticsCommunications BiologyPeer-reviewedMar 14, 2022

Artificial Intelligence-rationalized balanced PPARα/γ dual agonism resets the dysregulated macrophage processes in inflammatory bowel disease

Gajanan Dattatray Katkar, Ibrahim M. Sayed, Mahitha Shree Anandachar…·Pradipta Ghosh

The paper uses BoNE to identify dual PPARα/γ agonism as a therapeutic strategy for IBD, validated in preclinical models and patient-derived cells.

24 citations

mousebulk RNA-seq

𝕏 PostBluesky