Cancer BiologybioRxivPreprint
Subclonal IDH1/2 Mutations as a Targetable Vulnerability in Vascular Tumors
Dong-Min Yu, E L Lee, Gabriel J. Starrett…·Richard C Wang
This study identifies low-variant allele frequency IDH1/2 mutations in sporadic angiosarcoma and shows they drive tumorigenesis through non-cell-autonomous mechanisms, responding to ivosidenib treatment.
DOI 10.64898/2026.05.14.725132