NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness
Keiko Miyadera, Evelyn Santana, Karolina P. Roszak…·Gustavo David Aguirre
This paper demonstrates that AAV gene therapy targeting ON-bipolar cells in a canine model of LRIT3-CSNB significantly improves night vision and restores LRIT3 function.
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