Author

Judith A. Pate

Euan MacDonald Centre for Motor Neuron Disease Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jenna M. GregoryiD· 2 shared Judi O’ShaughnessyiD· 2 shared Olivia M. RifaiiD· 2 shared Barry W. McColliD· 1 shared Christopher R. SibleyiD· 1 shared Fergal M. WaldroniD· 1 shared James LongdeniD· 1 shared Karina McDadeiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Jenna M. GregoryORCID

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2 papers

Recent·Most cited

NeuroscienceThe Journal of PathologyPeer-reviewedSep 7, 2022

Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis

Olivia M. Rifai, James Longden, Judi O’Shaughnessy…·Jenna M. Gregory

The paper uses random forest modelling to identify microglial activation as a key classifier for C9orf72-related ALS and shows spatial FUS staining changes predict disease status.

21 citations

humanspatial transcriptomics

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NeurosciencebioRxivPreprintMar 17, 2022

pTDP-43 aggregates accumulate in the gut and other non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis

Samuel B. Pattle, Judi O’Shaughnessy, Olivia M. Rifai…·Jenna M. Gregory

The paper identifies pTDP-43 aggregates in non-CNS tissues of ALS patients prior to symptom onset, suggesting systemic pathology beyond the central nervous system.

1 citation

humanexperimental assay

𝕏 PostBluesky