Cell BiologybioRxivPreprint
G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics
Alexandra Mazharian, Ophélie Bertin, Amrita Sarkar…·Yotis A. Senis
This study introduces CAPRIs, bispecific antibodies that inhibit platelet activation by clustering G6B with ITAM receptors, showing effectiveness in preventing thrombus formation without causing bleeding.
5 citations